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Faculty Profile
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DR. KRISTOPHER H. McCONNELL
Assistant Professor of Biology
Phone: (334) 683-5279 | Email: kmcconnell@judson.edu | Office: Lowder 104
At Judson College since 2012 EDUCATION
AREAS OF EXPERTISE
Molecular genetics, biochemistry,
cell biology, microbiology, developmental biology
MEET THE PROFESSOR
Dr. McConnell was born in the Northeast corner of Montanaa and spent most of his childhood in the small town of Fairview (pop. 840). He received his Bachelor of Science in Biology from Southeast Missouri State University and immediately began graduate study at the University of Wisconsin – Madison. After receiving his Ph.D., Dr. McConnell performed postdoctoral research in the lab of Dr. Brian Calvi, first at Syracuse University, then at Indiana University in Bloomington. Dr. McConnell’s research has focused on the molecular mechanisms that regulate DNA replication. This is the process by which a cell’s genome is copied in preparation for cell division, and defects in this process contribute to the development of cancer. As a graduate student, Dr. McConnell originally studied this process in the single-celled fungus Saccharomyces cerevisiae, also known as baker’s yeast. For his postdoctoral research, Dr. McConnell continued to study DNA replication, using the fruit fly Drosophila melanogaster as a model system. Dr. McConnell has published multiple peer-reviewed journal articles describing this research. Dr. McConnell is married to Margarita Quinchia-Rios, of Medellin, Colombia, and they have one daughter, Victoria, age 2. Dr. McConnell is excited to use his expertise in the molecular mechanisms of biology in his classroom teaching at Judson. In addition, he is continuing to pursue research on DNA replication in the laboratory by mentoring undergraduate research projects. Please contact Dr. McConnell at kmcconnell@judson.edu if you are interested in studying biology at Judson College.
HONORS AND AWARDS
Governor’s Scholarship – Southeast Missouri State University 1996-2000 National Institutes of Health Predoctoral Training Grant – University of Wisconsin-Madison 2000-2003 National Institutes of Health Postdoctoral Fellowship – Syracuse University/Indiana University 2008-2011 PUBLICATIONS The histone acetyltransferases CBP and Chameau integrate developmental and DNA replication programs in Drosophila ovarian follicle cells. McConnell KH, Dixon M, Calvi BR. Development. 2012 Oct;139(20):3880-90. Analysis of model replication origins in Drosophila reveals new aspects of the chromatin landscape and its relationship to origin activity and the prereplicative complex. Liu J, McConnell K, Dixon M, Calvi BR. Mol Biol Cell. 2012 Jan;23(1):200-12. doi: 10.1091/mbc.E11-05-0409. A Dbf4p BRCA1 C-terminal-like domain required for the response to replication fork arrest in budding yeast. Gabrielse C, Miller CT, McConnell KH, DeWard A, Fox CA, Weinreich M. Genetics. 2006 Jun;173(2):541-55. Tolerance of Sir1p/origin recognition complex-dependent silencing for enhanced origin firing at HMRa. McConnell KH, Müller P, Fox CA. Mol Cell Biol. 2006 Mar;26(5):1955-66. Toward biochemical understanding of a transcriptionally silenced chromosomal domain in Saccharomyces cerevisiae. Fox CA, McConnell KH. J Biol Chem. 2005 Mar 11;280(10):8629-32. The origin recognition complex and Sir4 protein recruit Sir1p to yeast silent chromatin through independent interactions requiring a common Sir1p domain. Bose ME, McConnell KH, Gardner-Aukema KA, Müller U, Weinreich M, Keck JL, Fox CA. Mol Cell Biol. 2004 Jan;24(2):774-86.
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